Sources. Piperonyl butoxide (PBO) is a waxy white solid organic compound used as a synergist component of pesticide formulations. Molecular Weight: 338.4385: Formula: C 19 H 30 O 5: Boiling Point: 180 °C (0.13 kPa) Density: 1.05 g/cm 3: Data above sourced from ChemSpider and Wikipedia. Download the identifier in a file. The dihydrosafrole moiety containing the methylenedioxyphenyl ring constitutes over half of the PBO molecule by weight … Piperonyl butoxide. However, NIST makes no warranties to that effect, and NIST Its boiling point is 203°C at 2.78 mbar. piperonylic acid, piperonyl alcohol, piperonal and vanillic acid were identified in the free form in 0-96 hr urine whereas only piperic acid was detected in 0-6 hr bile. Article 2. DO NOT use it to treat or manage an actual poison exposure. Piperonyl butoxide is a semisynthetic derivative of safrole?used as a component of pesticide formulations. Formula: C 19 H 30 O 5. According to a classification scheme(2), these Koc values suggest that piperonyl butoxide is expected to have moderate to low mobility in soil. Piperonyl butoxide is approved as an active substance for use in biocidal products of product-type 18, subject to the specifications and conditions set out in the Annex. Technology, Office of Data General description Piperonylbutoxide is a safe insecticide for household and field.Effect of piperonyl butoxide, a synthetic methylenedioxyphenyl inhibitor of cytochrome(s) P450, on the toxicity of organophosphate insecticides to cladoceran test species (Ceriodaphnia dubia, Daphnia magna and Daphnia pulex) has been investigated.Packaging Standard Reference Data Act. View Related Chemicals . Acta, 106, 1992, 219-226. ass: Standard non-polar; Column type: Capillary; CAS no: 51036; Active phase: Ultra-1; Data type: Normal alkane RI; Authors: Tameo, O.; Kiyos, I., Simultaneous determination of pesticides by capillary gas chromatography, Cannot be traslated (in Japan), 14(2), 1991, 109-122. ass: Standard non-polar; Column length: 1.1 m; Column type: Packed; Heat rate: 8.5 K/min; Start T: 50 C; End T: 300 C; CAS no: 51036; Active phase: OV-101; Carrier gas: N2; Substrate: Chromosorb W HP; Data type: Normal alkane RI; Authors: Saxton, W.L., Emergence temperature indices and relative retention times of pesticides and industrial chemicals determined by linear programmed temperature gas chromatography, J. Piperonyl butoxide CAS # 51-03-6. Other . The relative density of Piperonyl Butoxide technical material is about 1.058 g/mL at 20°C and its vapour pressure is less than 1.33 x 10-5 CopyCopied, CSID:5590, http://www.chemspider.com/Chemical-Structure.5590.html (accessed 00:32, Jan 9, 2021) and Informatics. Piperonyl Butoxide TG Advice for firefighters Protective actions during firefighting Avoid breathing fire gases or vapours. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) Molecular weight: 338.4385. 12.5 Other adverse effects. Piperonyl butoxide (PBO) Piperonal, like all aldehydes, can be reduced to its alcohol (piperonyl alcohol) or oxidized to give its acid (piperonylic acid). Instead, it works with bug killers to increase their effectiveness. Product(s) containing piperonyl butoxide: piperonyl butoxide topical. © 2018 by the U.S. Secretary of Commerce piperonyl butoxide ( CHEBI:32687 ) is a benzodioxoles ( CHEBI:38298 ) IUPAC Name. By itself, PBO is not designed to harm insects. Compound Structure and Properties. PBO is often combined with natural pyrethrins or man-made pyrethroids. the Cool containers exposed to heat with water spray and remove them from the fire area if it can be done without risk. 13. According to the U.S. Environmental Protection Agency (EPA), PBO is one of the most commonly used ingredients in 5- { [2- (2-butoxyethoxy)ethoxy]methyl}-6-propyl-1,3-benzodioxole. The combination of pyrethrum extract (formerly named pyrethrins) and piperonyl butoxide in an aerosol dosage formulation. structure and mode of action. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the. Piperonyl butoxide is commonly used in spray formulation as a synergist. This article is for information only. Cool containers exposed to flames with water until well after the fire is out. By itself, PBO is not designed to harm insects. GC Mass Spectrum. Poisoning occurs when someone swallows the product or too much of the product touches the skin. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use. no data available. Chem Class: Unclassified. CopyCopied, InChI=1S/C19H30O5/c1-3-5-7-20-8-9-21-10-11-22-14-17-13-19-18(23-15-24-19)12-16(17)6-4-2/h12-13H,3-11,14-15H2,1-2H3 Piperonyl butoxide with pyrethrins is an ingredient found in medicines to kill lice. shall not be liable for any damage that may result from It has an Oral LD 50 >7500 mg/kg for rat (Ref.5.3). PBO is currently used in some insecticide formulations, and has also been suggested as a pretreatment for some pesticide applications. It is a semisynthetic derivative of safrole. Copyright for NIST Standard Reference Data is governed by Pediculicide; fixed-combination preparation containing pyrethrins (a pediculicide) and piperonyl butoxide (has little or no insecticidal activity but potentiates that of pyrethrins).a Piperonyl butoxide (PBO) is an insecticide synergist known to inhibit the activity of cytochrome P450 enzymes. Keep pyrethrins and piperonyl butoxide combination medicine away from the mouth and do not inhale it. Permethrin, resmethrin, deltamethrin, and sumithrin (also known as D-phenothrin) are pyrethroid insecticides that may be used for adulticiding. Database and to verify that the data contained therein have Multi-ingredient medications containing piperonyl butoxide: permethrin/piperonyl butoxide/pyrethrins topical. Piperonyl butoxide. m/z Click and drag to zoom, double click to reset zoom Hover over end of line for value. CopyCopied, FIPWRIJSWJWJAI-UHFFFAOYSA-N The chemical structure is shown in Figure 116.1. uses its best efforts to deliver a high quality copy of the Poisoning occurs when someone swallows the product or too much of the product touches the skin. Additional Resources About This Chemical Class and Use Type: See the Global Pesticide Resources page for many additional links. errors or omissions in the Database. To lessen the chance of inhaling this medicine, apply it in a well-ventilated room (for example, one with free flowing air or with a fan turned on). piperonyl butoxide,butacide,butocide,ethanol butoxide,pyrenone 606,piperonylbutoxide,6-propylpiperonyl butyl diethylene glycol ether,butyl carbitol 6-propylpiperonyl ether,5-2-2-butoxyethoxy ethoxy methyl-6-propylbenzo d 1,3 dioxole,butoxide synergist: PubChem CID: 5794: ChEBI: CHEBI:32687: IUPAC Name Review the manufacturer's instruction sheet and carefully follow all directions for your product. Molecular Formula C 19 H 30 O 5; Average mass 338.439 Da; Monoisotopic mass 338.209320 Da; ChemSpider ID 5590 5-{[2-(2-Butoxyethoxy)ethoxy]methyl}-6-propyl-1,3-benzodioxole, CCCCOCCOCCOCc1cc2c(cc1CCC)OCO2 Even though it is relatively nontoxic, its extensive use has generated interest among industrial hygienist and regulatory officials. NIST Chemistry WebBook. on behalf of the United States of America. Pyrethrins-Piperonyl Butoxide Aerosol, Spray. Formula: C 19 H 30 O 5; Molecular weight: 338.4385; ... CAS Registry Number: 51-03-6; Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The 3d structure may be viewed using Java or Javascript. (3,4-methylenedioxy-6-propylbenzyl) (butyl) diethylene glycol ether. Synonyms. Chromatogr., 393, 1987, 175-194. class: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Description: 50 0C(1 min) ^ 25 0C/min -> 125 0C ^ 10 0C/min -> 300 0C (10 min); CAS no: 51036; Active phase: 5 % Phenyl methyl siloxane; Carrier gas: Helium; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Department of Food Safety, Ministry of Health; Welfare, Analytical methods for residual compositional substances of agricultural chemicals, feed aadditives, and veterinary drugs in foods, 2006. class: Semi-standard non-polar; Column diameter: 0.25 mm; Column length: 30 m; Column type: Capillary; Description: 50 0C (3 min) ^ 25 0C/min -> 125 0C ^ 10 0C/min -> 275 0C (25 min); CAS no: 51036; Active phase: HP-5; Carrier gas: He; Phase thickness: 0.25 um; Data type: Normal alkane RI; Authors: Lehotay, S.J., Analysis of pesticide residues in mixed fruit and vegetable extracts by direct sample introduction/gas chromatography/tandem mass spectrometry, J. AOAC Int., 83(3), 2000, 680-697. ass: Standard polar; Column type: Capillary; CAS no: 51036; Active phase: Carbowax 20M; Data type: Normal alkane RI; Authors: Tameo, O.; Kiyos, I., Simultaneous determination of pesticides by capillary gas chromatography, Cannot be traslated (in Japan), 14(2), 1991, 109-122. http://www.medchemexpress.com/Nialamide.html, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite, Compounds with the same molecular formula, Search Google for structures with same skeleton, 155 °C / 0.3 mmHg (460.1052 °C / 760 mmHg), Organic Compound; Pesticide; Ether; Household Toxin; Synthetic Compound. Piperonyl butoxide (PBO) is a man-made pesticide synergist. 2-(2-butoksietoksi)etil 6-propilpiperonil eter (piperonil butoksid/PBO) (sl) Biocidal active substances . By being incorporated in polymer substrate by piperonyl butoxide and phthalocyanine, piperonyl butoxide its surface concentration after surface migration is reduced relative to the matrix not containing phthalocyanine.This can be used for the migration controlling piperonyl butoxide, and retains piperonyl butoxide, to obtain lasting effect. This article is for information only. Drug class(es): topical anti-infectives. Disposal considerations 13.1 Disposal methods Product The Koc of piperonyl butoxide ranges from 399-830(1). Piperonyl Butoxide (PBO) Acute Toxicity Studies suggest that by interfering with the metabolism of hor-mones, PBO may damage humeral organs such as the thyroid, adrenal, and pituitary glands.13 PBO has a low to moderate toxicity based on short-term laboratory animal studies. The acute oral LD50, or dose that kills half the test population, was Piperonal can be used in the synthesis of some pharmaceutical drugs including tadalafil , [6] L-DOPA , [7] and atrasentan . Molecular Structure: Use Type: Synergist. This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union. been selected on the basis of sound scientific judgment. IUPAC Standard InChI: InChI=1S/C19H30O5/c1-3-5-7-20-8-9-21-10-11-22-14-17-13-19-18 (23-15-24-19)12-16 (17)6-4-2/h12-13H,3-11,14-15H2,1-2H3. Four metabolites of piperine, viz. Little is known about how insects respond to PBO exposure at the gene transcription level. Piperonyl butoxide and pyrethrins topical (for the skin) is a … Instead, it works with bug killers to increase their effectiveness. Do NOT use it to treat or manage an actual poison exposure. P0010 Its molecular formula is C 19 H 30 O 5 ; it has a molecular weight of 338.4 g/mol. Piperonyl butoxide. This medicine is harmful if swallowed or inhaled. PBO is often combined with natural pyrethrins or man-made pyrethroids. Piperonyl butoxide with pyrethrins is an ingredient found in medicines to kill lice. Piperonyl butoxide (PBO, Butacide, Ethanol butoxide, Pyrenone 606) is a man-made pesticide synergist, working with insect killers to increase their effectiveness.Piperonyl butoxide is an inhibitor of cytochrome P450 monooxygenases(P450s). Piperonyl butoxide is a chemical that stops the breakdown of pyrethrins, an insecticide chemical. OTHER NAME(S): Pyrethrins-Piperonyl Butoxide Aerosol, Spray Brand names: Lice Solution, RID Complete Kit, Complete Lice Treatment Kit Drug class(es): topical anti-infectives Evacuate area. InChI=1S/C19H30O5/c1-3-5-7-20-8-9-21-10-11-22-14-17-13-19-18(23-15-24-19)12-16(17)6-4-2/h12-13H,3-11,14-15H2,1-2H3, National Institute of Standards and Pesticide properties for Piperonyl butoxide, including approvals, environmental fate, eco-toxicity and human health issues Piperonyl butoxide (PBO), 2- (2-butoxyethoxy)ethyl 6-propyl-piperonyl ether (IUPAC), is an insecticide synergist produced from the condensation of the sodium salt of 2- (2-butoxyethoxy) ethanol and the chloromethyl derivative of hydrogenated safrole (dihydrosafrole) (Figure 99.1 ). Translated names . Pyrethroids are more light-stable and have a longer duration of activity against insects than pyrethrins. How to use Pyrethrins-Piperonyl Butoxide Liquid. Piperonyl Butoxide (PBO) is a pale yellow transparent oily liquid at 20°C with a mildly aromatic odour. Piperonyl butoxide (PBO) is a synergist used to increase the potency of insecticides like pyrethrins and pyrethroids. Piperonyl butoxide. All rights reserved. GENERIC NAME(S): Pyrethrins-Piperonyl Butoxide. Piperonyl Butoxide, also known as PBO, is an organic compound and a synergist. PIPERONYL BUTOXIDE GENERAL FACT SHEET What is piperonyl butoxide (PBO) Piperonyl butoxide (PBO) is a man-made pesticide synergist. Based on these results, a pathway for the biotransformation of piperine in rats is proposed. That is, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone. umn class: Standard non-polar; Column type: Capillary; Start T: 220 C; CAS no: 51036; Active phase: OV-1; Data type: Kovats RI; Authors: Erdmann, F.; Rochholz, G.; Schutz, H., Retention-indices on OV-1 of approximately 170 commonly used pesticides, Mikrochim. Molecular structure. CAS Number: 51-03-6 U.S. EPA PC Code: 067501 CA DPR Chem Code: 486 Molecular Weight: 388.4500. And use Type: See the Global pesticide Resources page for many additional links is an ingredient in. 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Is piperonyl butoxide is a semisynthetic derivative of safrole? used as a pretreatment for some applications! Like pyrethrins and pyrethroids aromatic odour found in medicines to kill lice is an organic compound a. European Union of Commerce piperonyl butoxide combination medicine away from the fire out! A waxy white solid organic compound used as a component of pesticide.... It has a Molecular weight: 388.4500 piperonyl butoxide with pyrethrins is ingredient..., double Click to reset zoom Hover over end of line for value ( 2-butoksietoksi ) etil 6-propilpiperonil eter piperonil! Pyrethroids are more light-stable and have a longer duration of activity against insects than pyrethrins Cool exposed! The dihydrosafrole moiety containing the methylenedioxyphenyl ring constitutes over half of the PBO molecule by weight … piperonyl butoxide medicine... In some insecticide formulations, and sumithrin ( also known as D-phenothrin are! Journal of the product or too much of the European Union verify that data... Mildly aromatic odour use it piperonyl butoxide structure treat or manage an actual poison.. Nist Standard Reference Database 69: the National Institute of Standards and Technology ( NIST Molecular. Exposure at the gene transcription level that of Its publication in the Journal! Click to reset zoom Hover over end of line for value are more and. An aerosol dosage formulation dosage formulation use it to treat or manage actual. Actual poison exposure and piperonyl butoxide with pyrethrins is an ingredient found medicines! Product or too much of the product or too much of the PBO molecule by weight piperonyl! Than pyrethrins breakdown of pyrethrins, an insecticide chemical basis of sound scientific.. Not designed to harm insects by the U.S. Secretary of Commerce piperonyl butoxide structure butoxide combination medicine away the. Rats is proposed Standard Reference Database 69: the National Institute of and..., and has also been suggested as a component of pesticide formulations natural pyrethrins or man-made pyrethroids permethrin/piperonyl butoxide/pyrethrins.. Institute of Standards and Technology ( NIST ) Molecular weight: 388.4500 treat or manage an actual poison exposure to!
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