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Urine bioactivity, however, reflects a mixture of clindamycin and active metabolites, especially N-demethyl clindamycin and clindamycin sulfoxide. Kirby, J.C. Sherris and M. Turck. Federal (USA) law restricts this drug to use by or on the order of a licensed … Clindamycin is a semi-synthetic antibiotic produced by a 7 (S) - chloro-substitution of the 7 (R) -hydroxyl group of lincomycin, a naturally-produced antibiotic produced by Streptomyces lincolnensis var. 45:493-496, 1966. $10.87 6. Clindamycin hydrochloride (ANTIROBE AQUADROPS oral soluation) was tolerated with little evidence of toxicity in domestic shorthair cats when administered orally at 10× the minimum recommended therapeutic daily dose (11 mg/kg; 5 mg/lb) for 15 days, and at doses up to 5× the minimum recommended therapeutic dose for 42 … FREE shipping over $49 ANTIROBE capsules 75 mg - administer one (1) capsule every 12 hours for each 14 kg of body weight. Clindamycin, Found in Anitrobe Aquarops and Generic of Cleocin, Treats Cat and Dog Skin Problems and Respiratory Infections. Available for Android and iOS devices. Microbiology: The following clindamycin in vitro data are available but their clinical significance is unknown. 4. Anaerobic gram positive nonsporeforming bacilli, including: Propionibacterium, Eubacterium, Actinomyces species. Each mL of ANTIROBE AQUADROPS Liquid contains clindamycin hydrochloride equivalent to 25 mg clindamycin; and ethyl alcohol, 7.4%. Precautions. ANTIROBE AQUADROPS liquid - administer 2 mL (50 mg) every 12 hours for each 4.5 kg of body weight. Antibiotic (Clindamycin) Antirobe ... Cats - 5-15mg/lb every 24 hours for a maximum of 14 days. Canine Osteomyelitis: 11 mg/kg body weight every 12 hours. Dose of Antirobe Aquadrops to Cats 06 12 18 24 Time (hours) 0.1 1 10 Clindamycin Equivalent Activity (mcg/mL) Clindamycin Serum Concentrations 2.5 mg/lb (5.5 mg/kg) After B.I.D. Oral Dose of Antriobe Capsules to Dogs Clindamycin Serum Concentrations 5 mg/lb (11 mg/kg) After Single Oral Dose of Antirobe Aquadrops to Cats … Medicinal ingredient: Each mL contains clindamycin (as clindamycin hydrochloride) equivalent to 25 mg clindamycin and ethyl alcohol, 8.64%. During prolonged therapy of one month or greater, periodic liver and kidney function tests and … ANTIROBE Capsules and ANTIROBE AQUADROPS oral solution contain clindamycin hydrochloride which is the hydrated salt of clindamycin. ANTIROBE AQUADROPS Liquid (For Use in Dogs and Cats) is a palatable formulation intended for oral administration. Antirobe Aquadrops is available by prescription in oral dose solution. Antirobe created Antirobe Capsules for dogs, as well as Antirobot Aquadrops Liquid for dogs and cats—both of which are prescribed to help treat multiple infections. The following is a price list for the purchase of Antirobe Aquadrops 25mg/mL from our online pharmacy. ANTIROBE capsules 75 mg - each green and green capsule contains: Medicinal ingredient: clindamycin (as clindamycin hydrochloride) equivalent to 75 mg of clindamycin. Manitoba OELs (Reg. ANTIROBE capsules and ANTIROBE AQUADROPS liquid are contraindicated in animals with a history of hypersensitivity to preparations containing clindamycin or lincomycin. Susceptibility tests should be done on samples collected prior to initiation of therapy with ANTIROBE capsules or ANTIROBE AQUADROPS liquid. ANTIROBE AQUADROPS liquid is a palatable formulation intended for oral administration to dogs and cats. Each mL of ANTIROBE AQUADROPS contains clindamycin hydrochloride equivalent to 25 mg clindamycin. No copies ... PetsDrugMart only dispenses Health Canada approved prescription medication; and ships ONLY within Canada as long as a valid Canadian prescription has … Infected Wounds, Abscesses and Dental Infections: 5.5 mg/kg body weight every 12 hours. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Safety in gestating queens or breeding male cats has not been established. ANTIROBE AQUADROPS liquid is a palatable formulation intended for oral administration to dogs and cats. Differences did not occur in the parameters evaluated to assess toxicity when comparing groups of treated animals with contemporary controls. FREE shipping over $49 Continue Reading. ANTIROBE capsules 25 mg - each yellow and white capsule contains: Medicinal ingredient: clindamycin (as clindamycin hydrochloride) equivalent to 25 mg of clindamycin. The following is a price list for the purchase of Antirobe Aquadrops 25mg/mL from our online pharmacy. Canine: For treatment of infected wounds, abscesses and dental infections caused by or associated with Staphylococcus spp., Streptococcus spp., Bacteroides spp., Fusobacterium necrophorum and Clostridium perfringens and osteomyelitis caused by Staphylococcus aureus. $10.87 6. 1. The site of binding appears to be in the 50S sub-unit of the ribosome. Antirobe Aquadrops requires a prescription from your veterinarian. and Streptococcus spp. The problem with mixing it with the food is they often won’t eat … Infected Wounds, Abscesses, … No other effects were noted. Lymphocytic inflammation of the gallbladder was noted in a greater number of treated cats at the 110 mg/kg/day dose level than for control cats. Administration - Mouse 143 mg/kg, LD50 Oral Administration - Rat 2,618 mg/kg. Can i use antirobe aquadrops for my cat that has either a bladder infection or urinary tract infection - Answered by a verified Cat Veterinarian. Canada. Clindamycin is used in the treatment of soft tissue infections, dental infections and bone infections caused by susceptible strains of bacteria. Actions The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Updated: 2021-01-29. The biological half-life of clindamycin hydrochloride in feline serum is approximately 7.5 hours. No bioactivity accumulation occurs after multiple oral doses of clindamycin hydrochloride. Antirobe is an antibiotic and you want to know if you can mix it with your cat’s food. Site and Mode of Action: Clindamycin is an inhibitor of protein synthesis in the bacterial cell. Each mL of ANTIROBE AQUADROPS Liquid contains clindamycin hydrochloride equivalent to 25 mg clindamycin; and ethyl alcohol, 8.64%. Therefore, ANTIROBE AQUADROPS solution should be used with caution in animals receiving such agents. Treatment should not be continued for longer than 28 days if no response to therapy is seen. We use cookies to give you the best possible experience on our website. ANTIROBE AQUADROPS solution: Palatable formulation, each mL containing 25 mg clindamycin and ethyl alcohol, 8.64%. The answer is yes BUT….it is important that they take the medication – all of it. Using this method the laboratory can designate isolates as resistant, intermediate, or susceptible. DailyMed – antirobe aquadrops- clindamycin hydrochloride liquid Is wet or dry food better for cats Cats are notoriously picky … NOTE: Antirobe capsules are also available. Mycoplasma species: Most Mycoplasma species are susceptible to clindamycin. ANTIROBE capsules and ANTIROBE AQUADROPS liquid contain: Medicinal ingredient: Clindamycin (as clindamycin hydrochloride) which is the hydrated salt of clindamycin. This particular medication is one of the most commonly prescribed antibiotics for pets. Benefits: A … Treatment with ANTIROBE capsules or ANTIROBE AQUADROPS liquid may be continued up to a maximum of 28 days if clinical judgment indicates. ANTIROBE AQUADROPS Liquid (For Use in Dogs and Cats) is a palatable formulation intended for oral administration. (clindamycin hydrochloride capsules and solution - mfr. All trademarks and registered trademarks are the property of their respective owners. Clostridia: Most C. perfringens are susceptible, but other species, e.g., C. sporogenes and C. tertium are frequently resistant to clindamycin. Partial cross resistance has been demonstrated between clindamycin, erythromycin and macrolide antibiotics. Purchase Antirobe Clindamycin Hydrochloride Liquid 25Mg/mL of 20 mL bottle for dogs and cats at the lowest price. Learn more about Antirobe Clindamycin susceptibility testing is performed by using CLEOCIN Susceptibility Disks (clindamycin 2 µg) and CLEOCIN Susceptibility Powder 20 mg. A standardized disk testing procedure1 is recommended for determining susceptibility of aerobic bacteria to clindamycin. Antibiotic susceptibility testing by a standardized single disk method, Am. Treatment with ANTIROBE AQUADROPS liquid may be continued up to a maximum of 14 days if clinical judgement indicates. Key Benefits: Treats tissue … Each mL of ANTIROBE AQUADROPS Liquid contains clindamycin hydrochloride equivalent to 25 mg clindamycin; and ethyl alcohol, 7.4%. Pharmacia Animal Health, 40 Centennial Road, Orangeville, ON L9W 3T3, Registered Trademarks of Pharmacia & Upjohn Company: ANTIROBE, CLEOCIN, Registered Trademark of Pharmacia & Upjohn S.A.: AQUADROPS, Used under licence by Pharmacia Animal Health, DIN 00813575 (liquid), 00813532 (25 mg), 00813540 (75 mg), 00813524 (150 mg), Copyright © 2021 Animalytix LLC. Available in 20 mL … Each mL of Antirobe AQUADROPS Liquid contains clindamycin hydrochloride equivalent to 25 mg clindamycin; and ethyl alcohol, 8.64%. The biological half-life for clindamycin hydrochloride in dog serum is approximately, 5 hours. 5. The following is a price list for the purchase of Antirobe Aquadrops 25mg/mL from our online pharmacy. Cats Infected Wounds, Abscesses, and Dental Infections. Each mL of ANTIROBE AQUADROPS Liquid contains clindamycin hydrochloride equivalent to 25 mg clindamycin; and ethyl alcohol, 8.64%. A description is contained in the CLEOCIN Susceptibility Disk insert. Antirobe Aquadrops (Clindamycin HCl) Oral Solution for Dogs & Cats, 25 mg/mL, 20-mL . Binding occurs to the soluble RNA fraction of certain ribosomes, thereby inhibiting the binding of amino acids to those ribosomes. Duration: Treatment with Antirobe Aquadrops oral solution may be continued up to a … Oral Solution. ANTIROBE capsules 150 mg - administer one (1) capsule every 12 hours for each 14 kg of body weight. Antirobe Aquadrops (Clindamycin HCl) Oral Solution for Dogs & Cats, 25 mg/mL, 20-mL . For: Cats and Dogs. 3. Apart from these, the medicine is also found effective in the management of abscesses, bite wounds and respiratory infections in cats as well as dogs. Available in bottles of 200 capsules. 2. Path. The originating document has been archived. Available in bottles of 100 capsules. Partial cross resistance has been demonstrated between clindamycin, erythromycin and macrolide antibiotics. Posted by By Admin May 7, 2020 Posted in Uncategorized 270 Comments. Clindamycin is an … Antirobe Aquadrops (clindamycin drops) is an oral liquid antibiotic used to treat soft tissue, dental, and bone infections caused by susceptible strains of bacteria. ANTIROBE 150 mg, administer 2-6 capsules every 12 hours for each 60 pounds of body weight. This same study revealed that average peak serum concentrations occurred 1 hour and 15 minutes after dosing. Dogs and cats orally dosed with therapeutic amounts of clindamycin hydrochloride demonstrated antibacterial serum levels of the drug within 15 minutes post-dosing. ANTIROBE AQUADROPS Liquid (For Use in Dogs and Cats) is a palatable formulation intended for oral administration. This medicine requires valid prescription. ANTIROBE AQUADROPS liquid - to provide 11 mg/kg administer 0.5 mL/kg body weight once every 24 hours; to provide 22 mg/kg, administer 1 mL/kg body weight once every 24 hours. Feline Tissue Levels: Tissue concentrations measured at 10 days (µg/g; means) of clindamycin hydrochloride liquid in cats 2 hours after oral administration at 22 mg/kg body weight once every 24 hours for 10 days. Clindamycin hydrochloride has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. ANTIROBE AQUADROPS liquid - administer 1 mL (25 mg) every 12 hours for each 4.5 kg of body weight. When the directions in the CLEOCIN Susceptibility Powder insert are followed, a MIC (minimal inhibitory concentration) of 1.6 µg/mL may be considered susceptible; MICs of 1.6 to 4.8 µg/mL may be considered intermediate and MICs greater than 4.8 µg/mL may be considered resistant. The average peak serum concentration of clindamycin hydrochloride occurs about 1 hour after oral administration. ANTIROBE capsules 150 mg - each blue and white or blue and green capsule contains: Medicinal ingredient: clindamycin (as clindamycin hydrochloride) equivalent to 150 mg of clindamycin. 1Bauer, A.W., W.M. Feline: For treatment of infected wounds, abscesses and dental infections caused by or associated with Staphylococcus aureus, Staphylococcus intermedius, Streptococcus spp., Clostridium perfringens and Bacteroides fragilis. ANTIROBE AQUADROPS Liquid (For Use in Dogs and Cats) is a palatable formulation intended for oral administration. Antirobe understands the effect that infections can have on your pet’s livelihood. There was no bioactivity accumulation after a regimen of multiple oral doses. Feline Serum Levels: Therapeutically effective serum levels of clindamycin hydrochloride can be maintained by oral dosing at the rate of 11 - 22 mg/kg body weight once every 24 hours. Each mL of ANTIROBE AQUADROPS oral solution contains clindamycin hydrochloride equivalent to 25 mg clindamycin; and ethyl alcohol, 7.4%. J. Clin. Select one or more newsletters to continue. Clindamycin has been shown to have in vitro activity against isolates of the following organisms: Aerobic gram positive cocci, including: Staphylococcus aureus (penicillinase and non-penicillinase producing strains), Staphylococcus intermedius, Staphylococcus simulans, Staphylococcus epidermidis, streptococci (except S. faecalis), pneumococci. Antirobe AQUADROPS Liquid (For Use in Dogs and Cats) is a palatable formulation intended for oral administration. Veterinarians use this powerful antibiotic to treat abscesses, infected wounds and dental infections caused by bacteria including Staphylococcus spp. ANTIROBE capsules 25 mg - administer one (1) capsule every 12 hours for each 4.5 kg of body weight. ANTIROBE capsules 25 mg - administer one (1) capsule every 12 hours for each 2 kg of body weight. Partial cross resistance has been demonstrated between clindamycin, erythromycin and macrolide antibiotics. ANTIROBE AQUADROPS oral solution (For Use in Dogs and Cats) is a palatable formulation intended for oral administration. Read More. Antirobe (clindamycin hydrochloride) Zoetis US. Available in 20 mL bottles. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. ANTIROBE (Clindamycin Hydrochloride) Aquadrops Liquid by Pfizer helps combat infections in dogs and cats. That’s why they are committed to helping you provide the relief they need. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert. Rats administered clindamycin hydrochloride at 600 mg/kg/day for six months tolerated the drug well; however, dogs orally dosed at 600 mg/kg/day vomited, had anorexia, and subsequently lost weight. ... Direa tablets are a safe and palatable tablet to help in the treatment of diarrhoea and gas in dogs and cats. ANTIROBE AQUADROPS Liquid (For Use in Dogs and Cats) is a palatable formulation intended for oral administration. Available in bottles of 200 capsules. Copyright ©2002-2021 universalpetmeds.ca "Universal Pet Meds Canada™" and "universalpetmeds.ca" are registered trademarks of "Universal Pet Meds Canada™" All rights reserved. To. Because of potential adverse gastrointestinal effects, do not administer to rabbits, hamsters, guinea pigs, horses, chinchillas or ruminating animals. Antirobe Aquadrops For Cats & Dogs DIN: 00813575 Health Canada 'Drug Schedule': Prescription. Clindamycin hydrochloride (ANTIROBE AQUADROPS liquid) was well tolerated with little evidence of toxicity in domestic shorthair cats when administered orally at 10x the minimum recommended therapeutic daily dose of 11 mg/kg for 15 days, at doses up to 5x the minimum recommended therapeutic dose for 42 days. ANTIROBE 75 mg, administer 2-6 capsules every 12 hours for each 30 pounds of body weight. Treatment with ANTIROBE capsules or ANTIROBE AQUADROPS liquid is recommended for a minimum of 28 days. Animal toxicity studies with clindamycin hydrochloride showed the following: LD50 I.P. ANTIROBE AQUADROPS, administer 2-6 mL/ 10 lbs body weight every 12 hours. 30 pounds of body weight every 12 hours for a maximum of 14 days if clinical judgement indicates 75... Days if clinical judgement indicates to Dogs and Cats levels of the gallbladder was noted in greater. 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